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Disorder-to-order transition underlies the structural basis for the assembly of a transcriptionally...

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Disorder-to-order transition underlies the structural basis for the assembly of a transcriptionally...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1539447862

Disorder-to-order transition underlies the structural basis for the assembly of a transcriptionally active PGC-1α/ERRγ complex

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Full title

Disorder-to-order transition underlies the structural basis for the assembly of a transcriptionally active PGC-1α/ERRγ complex

Author / Creator

Devarakonda, Srikripa , Gupta, Kushol , Chalmers, Michael J , Hunt, John F , Griffin, Patrick R , Van Duyne, Gregory D and Spiegelman, Bruce M

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-11, Vol.108 (46 p.18678-18683), p.18678-18683

Language

English

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Scope and Contents

Contents

Peroxisome proliferator activated receptor (PPAR) γ coactivator-1α (PGC-1α) is a potent transcriptional coactivator of oxidative metabolism and is induced in response to a variety of environmental cues. It regulates a broad array of target genes by coactivating a whole host of transcription factors. The estrogen-related receptor (ERR) family of...

Alternative Titles

Full title

Disorder-to-order transition underlies the structural basis for the assembly of a transcriptionally active PGC-1α/ERRγ complex

Authors, Artists and Contributors

Author / Creator

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Record Identifier

TN_cdi_proquest_miscellaneous_1539447862

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1539447862

Other Identifiers

ISSN

0027-8424

DOI

10.1073/pnas.1113813108

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