Mutation or Loss of p53 Differentially Modifies TGF beta Action in Ovarian Cancer: e89553
Mutation or Loss of p53 Differentially Modifies TGF beta Action in Ovarian Cancer: e89553
About this item
Full title
Mutation or Loss of p53 Differentially Modifies TGF beta Action in Ovarian Cancer: e89553
Author / Creator
Journal title
PloS one, 2014-02, Vol.9 (2)
Language
English
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Scope and Contents
Contents
Ovarian cancer is the most lethal gynecological disease affecting women in the US. The Cancer Genome Atlas Network identified p53 mutations in 96% of high-grade serous ovarian carcinomas, demonstrating its critical role. Additionally, the Transforming Growth Factor Beta (TGF beta ) pathway is dysfunctional in various malignancies, including ovarian...
Alternative Titles
Full title
Mutation or Loss of p53 Differentially Modifies TGF beta Action in Ovarian Cancer: e89553
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1544004905
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1544004905
Other Identifiers
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0089553
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