Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial
Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial
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Author / Creator
Vermeire, Séverine, Dr , O'Byrne, Sharon, MD , Keir, Mary, PhD , Williams, Marna, PhD , Lu, Timothy T, MD , Mansfield, John C, MD , Lamb, Christopher A, MD , Feagan, Brian G, MD , Panes, Julian, MD , Salas, Azucena, PhD , Baumgart, Daniel C, MD , Schreiber, Stefan, MD , Dotan, Iris, MD , Sandborn, William J, MD , Tew, Gaik W, MSc , Luca, Diana, PhD , Tang, Meina T, PhD , Diehl, Lauri, DVM , Eastham-Anderson, Jeffrey, MS , De Hertogh, Gert, MD , Perrier, Clementine, PhD , Egen, Jackson G, PhD , Kirby, John A, PhD , van Assche, Gert, MD and Rutgeerts, Paul, MD
Publisher
Kidlington: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
Kidlington: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Etrolizumab is a humanised monoclonal antibody that selectively binds the β7 subunit of the heterodimeric integrins α4β7 and αEβ7. We aimed to assess etrolizumab in patients with moderately-to-severely active ulcerative colitis. Methods In this double-blind, placebo-controlled, randomised, phase 2 study, patients with moderately-...
Alternative Titles
Full title
Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial
Authors, Artists and Contributors
Author / Creator
O'Byrne, Sharon, MD
Keir, Mary, PhD
Williams, Marna, PhD
Lu, Timothy T, MD
Mansfield, John C, MD
Lamb, Christopher A, MD
Feagan, Brian G, MD
Panes, Julian, MD
Salas, Azucena, PhD
Baumgart, Daniel C, MD
Schreiber, Stefan, MD
Dotan, Iris, MD
Sandborn, William J, MD
Tew, Gaik W, MSc
Luca, Diana, PhD
Tang, Meina T, PhD
Diehl, Lauri, DVM
Eastham-Anderson, Jeffrey, MS
De Hertogh, Gert, MD
Perrier, Clementine, PhD
Egen, Jackson G, PhD
Kirby, John A, PhD
van Assche, Gert, MD
Rutgeerts, Paul, MD
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1549199078
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1549199078
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(14)60661-9
