IL-17-producing CD4−CD8− T cells are expanded in the peripheral blood, infiltrate salivary glands an...
IL-17-producing CD4−CD8− T cells are expanded in the peripheral blood, infiltrate salivary glands and are resistant to corticosteroids in patients with primary Sjögren's syndrome
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Publisher
London: BMJ Publishing Group Ltd and European League Against Rheumatism
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Language
English
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Publisher
London: BMJ Publishing Group Ltd and European League Against Rheumatism
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Contents
Objectives It has been recently observed that a T-cell subset, lacking of both CD4 and CD8 molecules and defined as double negative (DN), is expanded in the blood of patients with systemic lupus erythematosus, produces IL-17 and accumulates in the kidney during nephritis. Since IL-17 production is enhanced in salivary gland infiltrates of primary S...
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Full title
IL-17-producing CD4−CD8− T cells are expanded in the peripheral blood, infiltrate salivary glands and are resistant to corticosteroids in patients with primary Sjögren's syndrome
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Record Identifier
TN_cdi_proquest_miscellaneous_1551619861
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1551619861
Other Identifiers
ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2012-201511