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iPLA2β Knockout Mouse, a Genetic Model for Progressive Human Motor Disorders, Develops Age-Related N...

iPLA2β Knockout Mouse, a Genetic Model for Progressive Human Motor Disorders, Develops Age-Related N...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1551820551

iPLA2β Knockout Mouse, a Genetic Model for Progressive Human Motor Disorders, Develops Age-Related Neuropathology

About this item

Full title

iPLA2β Knockout Mouse, a Genetic Model for Progressive Human Motor Disorders, Develops Age-Related Neuropathology

Publisher

Boston: Springer US

Journal title

Neurochemical research, 2014-08, Vol.39 (8), p.1522-1532

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

Calcium-independent phospholipase A
2
group VIa (iPLA
2
β) preferentially releases docosahexaenoic acid (DHA) from the
sn
-
2
position of phospholipids. Mutations of its gene, PLA2G6, are found in patients with several progressive motor disorders, including Parkinson disease. At 4 months, PLA2G6 knockout mice (iPLA
2
β...

Alternative Titles

Full title

iPLA2β Knockout Mouse, a Genetic Model for Progressive Human Motor Disorders, Develops Age-Related Neuropathology

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1551820551

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1551820551

Other Identifiers

ISSN

0364-3190

E-ISSN

1573-6903

DOI

10.1007/s11064-014-1342-y

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