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Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for su...

Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for su...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1554943251

Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival

About this item

Full title

Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2014-01, Vol.17 (1), p.36-45

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

In this study, the authors report that target-derived NGF signaling induces the expression of Coronin-1, which consequently gets recruited to the NGF-TrkA–carrying signaling endosome, where it regulates endosomal fusion with lysosomes, trafficking and recycling. In addition, Coronin-1 appears to be necessary for NGF-dependent signaling events such...

Alternative Titles

Full title

Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1554943251

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1554943251

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/nn.3593

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