The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T...
The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells
About this item
Full title
Author / Creator
Obata, Yuuki , Furusawa, Yukihiro , Endo, Takaho A , Sharif, Jafar , Takahashi, Daisuke , Atarashi, Koji , Nakayama, Manabu , Onawa, Satoshi , Fujimura, Yumiko , Takahashi, Masumi , Ikawa, Tomokatsu , Otsubo, Takeshi , Kawamura, Yuki I , Dohi, Taeko , Tajima, Shoji , Masumoto, Hiroshi , Ohara, Osamu , Honda, Kenya , Hori, Shohei , Ohno, Hiroshi , Koseki, Haruhiko and Hase, Koji
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Regulatory T cells proliferate robustly in gut lymphoid tissues. Hase
et al
. show that this proliferation requires their expression of the epigenetic regulator Uhrf1, which is increased in response to IL-2 produced by effector T cells.
Intestinal regulatory T cells (T
reg
cells) are necessary for the suppression of excessive immune...
Alternative Titles
Full title
The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells
Authors, Artists and Contributors
Author / Creator
Furusawa, Yukihiro
Endo, Takaho A
Sharif, Jafar
Takahashi, Daisuke
Atarashi, Koji
Nakayama, Manabu
Onawa, Satoshi
Fujimura, Yumiko
Takahashi, Masumi
Ikawa, Tomokatsu
Otsubo, Takeshi
Kawamura, Yuki I
Dohi, Taeko
Tajima, Shoji
Masumoto, Hiroshi
Ohara, Osamu
Honda, Kenya
Hori, Shohei
Ohno, Hiroshi
Koseki, Haruhiko
Hase, Koji
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1554945803
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1554945803
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2886
