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A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical app...

A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical app...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1554946494

A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application

About this item

Full title

A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2013-12, Vol.14 (12), p.1212-1218

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

PD-1, a negative coreceptor expressed on antigen-stimulated T cells and B cells, seems to serve as a 'rheostat' of the immune response. The molecular mechanisms of the functions of PD-1, in conjunction with the mild, chronic and strain-specific autoimmune phenotypes of PD-1-deficient mice, in contrast to the devastating fatal autoimmune disease of...

Alternative Titles

Full title

A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1554946494

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1554946494

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.2762

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