The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy
The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy
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Author / Creator
Burchell, Victoria S , Nelson, David E , Sanchez-Martinez, Alvaro , Delgado-Camprubi, Marta , Ivatt, Rachael M , Pogson, Joe H , Randle, Suzanne J , Wray, Selina , Lewis, Patrick A , Houlden, Henry , Abramov, Andrey Y , Hardy, John , Wood, Nicholas W , Whitworth, Alexander J , Laman, Heike and Plun-Favreau, Helene
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Mutations in the gene encoding the F-box domain–containing protein Fbxo7 are genetically associated to an autosomal recessive form of early-onset Parkinson's disease of similar severity to those caused by Parkinson's disease–linked mutations in the genes for the mitochondrial kinase PINK1 or the E3 ubiquitin ligase Parkin. Burchell
et al
. sh...
Alternative Titles
Full title
The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy
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TN_cdi_proquest_miscellaneous_1554947076
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1554947076
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.3489
