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The adaptor TRAF5 limits the differentiation of inflammatory CD4 super(+) T cells by antagonizing si...

The adaptor TRAF5 limits the differentiation of inflammatory CD4 super(+) T cells by antagonizing si...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1554953536

The adaptor TRAF5 limits the differentiation of inflammatory CD4 super(+) T cells by antagonizing signaling via the receptor for IL-6

About this item

Full title

The adaptor TRAF5 limits the differentiation of inflammatory CD4 super(+) T cells by antagonizing signaling via the receptor for IL-6

Journal title

Nature immunology, 2014-05, Vol.15 (5), p.449-456

Language

English

Formats

More information

Scope and Contents

Contents

The physiological functions of members of the tumor-necrosis factor (TNF) receptor (TNFR)-associated factor (TRAF) family in T cell immunity are not well understood. We found that in the presence of interleukin 6 (IL-6), naive TRAF5-deficient CD4 super(+) T cells showed an enhanced ability to differentiate into the T sub(H)17 subset of helper T cel...

Alternative Titles

Full title

The adaptor TRAF5 limits the differentiation of inflammatory CD4 super(+) T cells by antagonizing signaling via the receptor for IL-6

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1554953536

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1554953536

Other Identifiers

ISSN

1529-2908

DOI

10.1038/ni.2863

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