K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production...
K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5
About this item
Full title
Author / Creator
Harikumar, Kuzhuvelil B , Yester, Jessie W , Surace, Michael J , Oyeniran, Clement , Price, Megan M , Huang, Wei-Ching , Hait, Nitai C , Allegood, Jeremy C , Yamada, Akimitsu , Kong, Xiangqian , Lazear, Helen M , Bhardwaj, Reetika , Takabe, Kazuaki , Diamond, Michael S , Luo, Cheng , Milstien, Sheldon , Spiegel, Sarah and Kordula, Tomasz
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
IL-1 triggers IRF1 signaling, but the biological importance of this has remained uncertain. Kordula and colleagues show that an IL-1–IRF1 pathway is necessary for the selective induction of chemokines and sterile inflammation.
Although interleukin 1 (IL-1) induces expression of the transcription factor IRF1 (interferon-regulatory factor 1), the...
Alternative Titles
Full title
K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5
Authors, Artists and Contributors
Author / Creator
Yester, Jessie W
Surace, Michael J
Oyeniran, Clement
Price, Megan M
Huang, Wei-Ching
Hait, Nitai C
Allegood, Jeremy C
Yamada, Akimitsu
Kong, Xiangqian
Lazear, Helen M
Bhardwaj, Reetika
Takabe, Kazuaki
Diamond, Michael S
Luo, Cheng
Milstien, Sheldon
Spiegel, Sarah
Kordula, Tomasz
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1554954103
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1554954103
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2810
