Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-as...
Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin
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Author / Creator
Mauer, Jan , Chaurasia, Bhagirath , Goldau, Julia , Vogt, Merly C , Ruud, Johan , Nguyen, Khoa D , Theurich, Sebastian , Hausen, A Christine , Schmitz, Joel , Brönneke, Hella S , Estevez, Emma , Allen, Tamara L , Mesaros, Andrea , Partridge, Linda , Febbraio, Mark A , Chawla, Ajay , Wunderlich, F Thomas and Brüning, Jens C
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The role of IL-6 in obesity-associated inflammation remains controversial. Bruening and colleagues identify signaling by IL-6 as an important determinant for the alternative activation of macrophages during inflammation.
Obesity and resistance to insulin are closely associated with the development of low-grade inflammation. Interleukin 6 (IL-6)...
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Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin
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TN_cdi_proquest_miscellaneous_1554954131
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1554954131
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2865
