Effects of DNA damage and short-term spindle disruption on oocyte meiotic maturation
Effects of DNA damage and short-term spindle disruption on oocyte meiotic maturation
About this item
Full title
Author / Creator
Zhang, T. , Zhang, G. L. , Ma, J. Y. , Qi, S. T. , Wang, Z. B. , Wang, Z. W. , Luo, Y. B. , Jiang, Z. Z. , Schatten, H. and Sun, Q. Y.
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
DNA damage has recently been shown to inhibit or delay germinal vesicle breakdown (GVBD) in mouse oocytes, but once meiosis resumes, DNA-damaged oocytes are able to extrude the first polar body. In this study, using porcine oocytes, we showed that DNA damage did not affect GVBD, but inhibited the final stages of maturation, as indicated by failure...
Alternative Titles
Full title
Effects of DNA damage and short-term spindle disruption on oocyte meiotic maturation
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1560124674
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1560124674
Other Identifiers
ISSN
0948-6143
E-ISSN
1432-119X
DOI
10.1007/s00418-014-1182-5
