Orexin (Hypocretin) Receptor Agonists and Antagonists for Treatment of Sleep Disorders: Rationale fo...
Orexin (Hypocretin) Receptor Agonists and Antagonists for Treatment of Sleep Disorders: Rationale for Development and Current Status
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Cham: Springer International Publishing AG
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Language
English
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Cham: Springer International Publishing AG
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Contents
Orexin A and orexin B are hypothalamic neuropeptides initially identified as endogenous ligands for two orphan G-protein coupled receptors (GPCRs). They play critical roles in the maintenance of wakefulness by regulating function of monoaminergic and cholinergic neurons that are implicated in the regulation of wakefulness. Loss of orexin neurons in...
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Full title
Orexin (Hypocretin) Receptor Agonists and Antagonists for Treatment of Sleep Disorders: Rationale for Development and Current Status
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TN_cdi_proquest_miscellaneous_1560136944
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1560136944
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ISSN
1172-7047
E-ISSN
1179-1934
DOI
10.1007/s40263-012-0036-8
