Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-...
Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal
About this item
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Author / Creator
Fares, Iman , Chagraoui, Jalila , Gareau, Yves , Gingras, Stéphane , Ruel, Réjean , Mayotte, Nadine , Csaszar, Elizabeth , Knapp, David J H F , Miller, Paul , Ngom, Mor , Imren, Suzan , Roy, Denis-Claude , Watts, Kori L , Kiem, Hans-Peter , Herrington, Robert , Iscove, Norman N , Humphries, R Keith , Eaves, Connie J , Cohen, Sandra , Marinier, Anne , Zandstra, Peter W and Sauvageau, Guy
Publisher
United States
Journal title
Language
English
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Publication information
Publisher
United States
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Scope and Contents
Contents
The small number of hematopoietic stem and progenitor cells in cord blood units limits their widespread use in human transplant protocols. We identified a family of chemically related small molecules that stimulates the expansion ex vivo of human cord blood cells capable of reconstituting human hematopoiesis for at least 6 months in immunocompromis...
Alternative Titles
Full title
Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal
Authors, Artists and Contributors
Author / Creator
Chagraoui, Jalila
Gareau, Yves
Gingras, Stéphane
Ruel, Réjean
Mayotte, Nadine
Csaszar, Elizabeth
Knapp, David J H F
Miller, Paul
Ngom, Mor
Imren, Suzan
Roy, Denis-Claude
Watts, Kori L
Kiem, Hans-Peter
Herrington, Robert
Iscove, Norman N
Humphries, R Keith
Eaves, Connie J
Cohen, Sandra
Marinier, Anne
Zandstra, Peter W
Sauvageau, Guy
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1563985711
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1563985711
Other Identifiers
E-ISSN
1095-9203
DOI
10.1126/science.1256337