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Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-...

Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1563985711

Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal

About this item

Full title

Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal

Publisher

United States

Journal title

Science (American Association for the Advancement of Science), 2014-09, Vol.345 (6203), p.1509-1512

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

The small number of hematopoietic stem and progenitor cells in cord blood units limits their widespread use in human transplant protocols. We identified a family of chemically related small molecules that stimulates the expansion ex vivo of human cord blood cells capable of reconstituting human hematopoiesis for at least 6 months in immunocompromis...

Alternative Titles

Full title

Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1563985711

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1563985711

Other Identifiers

E-ISSN

1095-9203

DOI

10.1126/science.1256337

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