CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos
CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos
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Author / Creator
Shao, Yanjiao , Guan, Yuting , Wang, Liren , Qiu, Zhongwei , Liu, Meizhen , Chen, Yuting , Wu, Lijuan , Li, Yongmei , Ma, Xueyun , Liu, Mingyao and Li, Dali
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Genetic techniques in rats are developing apace. Here, Shao
et al
. describe how to use CRISPR/Cas-mediated genome editing to modify one-cell rat embryos and generate stable rat lines.
Conventional embryonic stem cell (ESC)–based gene targeting, zinc-finger nuclease (ZFN) and transcription activator–like effector nuclease (TALEN) technolog...
Alternative Titles
Full title
CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_1566408351
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1566408351
Other Identifiers
ISSN
1754-2189
E-ISSN
1750-2799
DOI
10.1038/nprot.2014.171
