Human Brain Imaging of alpha 7 nAChR with [ super(18)F]ASEM: a New PET Radiotracer for Neuropsychiat...
Human Brain Imaging of alpha 7 nAChR with [ super(18)F]ASEM: a New PET Radiotracer for Neuropsychiatry and Determination of Drug Occupancy
About this item
Full title
Author / Creator
Journal title
Language
English
Formats
Subjects
More information
Scope and Contents
Contents
Purpose: Using the alpha 7-nAChR radiotracer, [ super(18)F]ASEM, we present the first successful human positron emission tomography (PET) studies. Rodent occupancy with three clinically employed alpha 7-nAChR drugs confirms the specificity of the radiotracer. Procedures: Five healthy male subjects were imaged for 90 min following IV [ super(18)F]AS...
Alternative Titles
Full title
Human Brain Imaging of alpha 7 nAChR with [ super(18)F]ASEM: a New PET Radiotracer for Neuropsychiatry and Determination of Drug Occupancy
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1566842188
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1566842188
Other Identifiers
ISSN
1536-1632
E-ISSN
1860-2002
DOI
10.1007/s11307-014-0779-3
