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Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells

Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1566844665

Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells

About this item

Full title

Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2014-08, Vol.16 (8), p.779-791

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Chromosomal instability (CIN) is defined as the perpetual missegregation of whole chromosomes during mitosis and represents a hallmark of human cancer. However, the mechanisms influencing CIN and its consequences on tumour growth are largely unknown. We identified an increase in microtubule plus-end assembly rates as a mechanism influencing CIN in...

Alternative Titles

Full title

Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1566844665

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1566844665

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/ncb2994

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