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Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tiss...

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tiss...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_16106808

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues

About this item

Full title

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1997-06, Vol.94 (13), p.7001-7005

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Leptin's effects are mediated by interactions with a receptor that is alternatively spliced, resulting in at least five different murine forms: Ob-Ra, Ob-Rb, Ob-Rc, Ob-Rd, and Ob-Re. A mutation in one splice form, Ob-Rb, results in obesity in mice. Northern blots, RNase protection assays, and PCR indicate that Ob-Rb is expressed at a relatively hig...

Alternative Titles

Full title

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_16106808

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_16106808

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.94.13.7001

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