Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tiss...
Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues
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United States: National Academy of Sciences of the United States of America
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Language
English
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United States: National Academy of Sciences of the United States of America
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Contents
Leptin's effects are mediated by interactions with a receptor that is alternatively spliced, resulting in at least five different murine forms: Ob-Ra, Ob-Rb, Ob-Rc, Ob-Rd, and Ob-Re. A mutation in one splice form, Ob-Rb, results in obesity in mice. Northern blots, RNase protection assays, and PCR indicate that Ob-Rb is expressed at a relatively hig...
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Full title
Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues
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TN_cdi_proquest_miscellaneous_16106808
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_16106808
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.94.13.7001