Coadministration of Branched-Chain Amino Acids and Lipopolysaccharide Causes Matrix Metalloproteinas...
Coadministration of Branched-Chain Amino Acids and Lipopolysaccharide Causes Matrix Metalloproteinase Activation and Blood–Brain Barrier Breakdown
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Author / Creator
Scaini, Giselli , Morais, Meline O. S. , Galant, Leticia S. , Vuolo, Francieli , Dall’Igna, Dhébora M. , Pasquali, Matheus A. B. , Ramos, Vitor M. , Gelain, Daniel P. , Moreira, Jose Claudio F. , Schuck, Patrícia F. , Ferreira, Gustavo C. , Soriano, Francisco G. , Dal-Pizzol, Felipe and Streck, Emilio L.
Publisher
Boston: Springer US
Journal title
Language
English
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Publisher
Boston: Springer US
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Scope and Contents
Contents
Maple syrup urine disease (MSUD) is an inborn error of metabolism caused by a severe deficiency in the activity of the branched-chain α-keto acid dehydrogenase complex, leading to accumulation of the branched-chain amino acids (BCAA) leucine, isoleucine, and valine. Infections have a significant role in precipitating acute metabolic decompensation...
Alternative Titles
Full title
Coadministration of Branched-Chain Amino Acids and Lipopolysaccharide Causes Matrix Metalloproteinase Activation and Blood–Brain Barrier Breakdown
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Record Identifier
TN_cdi_proquest_miscellaneous_1611614486
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1611614486
Other Identifiers
ISSN
0893-7648
E-ISSN
1559-1182
DOI
10.1007/s12035-013-8618-0