SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer...
SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Natural killer (NK) cells are cytotoxic innate lymphoid cells that are involved in immune defense. NK cell reactivity is controlled in part by MHC class I recognition by inhibitory receptors, but the underlying molecular mechanisms remain undefined. Using a mouse model of conditional deletion in NK cells, we show here that the protein tyrosine phos...
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SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer cells
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TN_cdi_proquest_miscellaneous_1619314553
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1619314553
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms6108