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SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer...

SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1619314553

SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer cells

About this item

Full title

SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2014-10, Vol.5 (1), p.5108-5108, Article 5108

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Natural killer (NK) cells are cytotoxic innate lymphoid cells that are involved in immune defense. NK cell reactivity is controlled in part by MHC class I recognition by inhibitory receptors, but the underlying molecular mechanisms remain undefined. Using a mouse model of conditional deletion in NK cells, we show here that the protein tyrosine phos...

Alternative Titles

Full title

SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1619314553

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1619314553

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms6108

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