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Pten deletion in RIP-Cre neurons protects against type 2 diabetes by activating the anti-inflammator...

Pten deletion in RIP-Cre neurons protects against type 2 diabetes by activating the anti-inflammator...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1622610373

Pten deletion in RIP-Cre neurons protects against type 2 diabetes by activating the anti-inflammatory reflex

About this item

Full title

Pten deletion in RIP-Cre neurons protects against type 2 diabetes by activating the anti-inflammatory reflex

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2014-05, Vol.20 (5), p.484-492

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

A new study by Minna Woo and colleagues shows that a neuronal relay from the brain to the adipose tissue regulates whole-body insulin sensitivity by affecting macrophage function, and thus inflammation, in the periphery. These results suggest that a centrally mediated anti-inflammatory reflex exists to regulate metabolic health.
Inflammation has...

Alternative Titles

Full title

Pten deletion in RIP-Cre neurons protects against type 2 diabetes by activating the anti-inflammatory reflex

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1622610373

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1622610373

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.3527

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