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Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezom...

Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezom...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1622610636

Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma

About this item

Full title

Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma

Publisher

London: Nature Publishing Group UK

Journal title

Leukemia, 2014-10, Vol.28 (10), p.2049-2059

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Bortezomib therapy has shown promising clinical activity in mantle cell lymphoma (MCL), but the development of resistance to proteasome inhibition may limit its efficacy. To unravel the factors involved in the acquisition of bortezomib resistance
in vivo
, immunodeficient mice were engrafted with a set of MCL cell lines with different levels...

Alternative Titles

Full title

Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1622610636

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1622610636

Other Identifiers

ISSN

0887-6924

E-ISSN

1476-5551

DOI

10.1038/leu.2014.106

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