High mobility group box 1 in the inflammatory pathogenesis of epilepsy: profiling circulating levels...
High mobility group box 1 in the inflammatory pathogenesis of epilepsy: profiling circulating levels after experimental and clinical seizures
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London: Elsevier Ltd
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English
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London: Elsevier Ltd
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Abstract Background High mobility group box 1 (HMGB1) is a chromatin binding protein that is passively released by necrotic cells and actively secreted in response to inflammatory stimuli in a hyperacetylated form. HMGB1 is upregulated in the brain after injury and can regulate localised inflammatory reactions resulting in seizures. Antiepileptic d...
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High mobility group box 1 in the inflammatory pathogenesis of epilepsy: profiling circulating levels after experimental and clinical seizures
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TN_cdi_proquest_miscellaneous_1622611130
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1622611130
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ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(14)60368-8
