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HER2 heterogeneity affects trastuzumab responses and survival in patients with HER2-positive metasta...

HER2 heterogeneity affects trastuzumab responses and survival in patients with HER2-positive metasta...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1624933854

HER2 heterogeneity affects trastuzumab responses and survival in patients with HER2-positive metastatic breast cancer

About this item

Full title

HER2 heterogeneity affects trastuzumab responses and survival in patients with HER2-positive metastatic breast cancer

Publisher

England: Oxford University Press

Journal title

American journal of clinical pathology, 2014-12, Vol.142 (6), p.755-766

Language

English

Formats

Publication information

Publisher

England: Oxford University Press

More information

Scope and Contents

Contents

Heterogeneity of HER2 gene amplification is found in a subset of breast cancers. We investigated the impact of HER2 heterogeneity on trastuzumab responses and clinical outcomes in 112 patients with HER2-positive metastatic breast cancer.
Regional and genetic heterogeneity of HER2 gene amplification was determined in three different areas of each...

Alternative Titles

Full title

HER2 heterogeneity affects trastuzumab responses and survival in patients with HER2-positive metastatic breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1624933854

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1624933854

Other Identifiers

ISSN

0002-9173

E-ISSN

1943-7722

DOI

10.1309/AJCPIRL4GUVGK3YX

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