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PP2A and Aurora differentially modify Cdc13 to promote telomerase release from telomeres at G2/M pha...

PP2A and Aurora differentially modify Cdc13 to promote telomerase release from telomeres at G2/M pha...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1624935043

PP2A and Aurora differentially modify Cdc13 to promote telomerase release from telomeres at G2/M phase

About this item

Full title

PP2A and Aurora differentially modify Cdc13 to promote telomerase release from telomeres at G2/M phase

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2014-11, Vol.5 (1), p.5312, Article 5312

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

In yeast, the initiation of telomere replication at the late S phase involves in combined actions of kinases on Cdc13, the telomere binding protein. Cdc13 recruits telomerase to telomeres through its interaction with Est1, a component of telomerase. However, how cells terminate the function of telomerase at G2/M is still elusive. Here we show that...

Alternative Titles

Full title

PP2A and Aurora differentially modify Cdc13 to promote telomerase release from telomeres at G2/M phase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1624935043

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1624935043

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms6312

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