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Lysophospholipids secreted by splenic macrophages induce chemotherapy resistance via interference wi...

Lysophospholipids secreted by splenic macrophages induce chemotherapy resistance via interference wi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1624935434

Lysophospholipids secreted by splenic macrophages induce chemotherapy resistance via interference with the DNA damage response

About this item

Full title

Lysophospholipids secreted by splenic macrophages induce chemotherapy resistance via interference with the DNA damage response

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2014-11, Vol.5 (1), p.5275-5275, Article 5275

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Host responses to systemic anti-cancer treatment play important roles in the development of anti-cancer drug resistance. Here we show that F4/80
+
/CD11b
low
splenocytes mediate the resistance to DNA-damaging chemotherapeutics induced by two platinum-induced fatty acids (PIFAs), 12-S-keto-5,8,10-heptadecatrienoic acid and 4,7,10,13-hexa...

Alternative Titles

Full title

Lysophospholipids secreted by splenic macrophages induce chemotherapy resistance via interference with the DNA damage response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1624935434

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1624935434

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms6275

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