Intravenously injected Newcastle disease virus in non-human primates is safe to use for oncolytic vi...
Intravenously injected Newcastle disease virus in non-human primates is safe to use for oncolytic virotherapy
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Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Newcastle disease virus (NDV) is an avian paramyxovirus with oncolytic potential. Detailed preclinical information regarding the safety of oncolytic NDV is scarce. In this study, we evaluated the toxicity, biodistribution and shedding of intravenously injected oncolytic NDVs in non-human primates (
Macaca fascicularis)
. Two animals were inje...
Alternative Titles
Full title
Intravenously injected Newcastle disease virus in non-human primates is safe to use for oncolytic virotherapy
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Record Identifier
TN_cdi_proquest_miscellaneous_1635025881
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1635025881
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ISSN
0929-1903
E-ISSN
1476-5500
DOI
10.1038/cgt.2014.51