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Intravenously injected Newcastle disease virus in non-human primates is safe to use for oncolytic vi...

Intravenously injected Newcastle disease virus in non-human primates is safe to use for oncolytic vi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1635025881

Intravenously injected Newcastle disease virus in non-human primates is safe to use for oncolytic virotherapy

About this item

Full title

Intravenously injected Newcastle disease virus in non-human primates is safe to use for oncolytic virotherapy

Publisher

New York: Nature Publishing Group US

Journal title

Cancer gene therapy, 2014-11, Vol.21 (11), p.463-471

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Newcastle disease virus (NDV) is an avian paramyxovirus with oncolytic potential. Detailed preclinical information regarding the safety of oncolytic NDV is scarce. In this study, we evaluated the toxicity, biodistribution and shedding of intravenously injected oncolytic NDVs in non-human primates (
Macaca fascicularis)
. Two animals were inje...

Alternative Titles

Full title

Intravenously injected Newcastle disease virus in non-human primates is safe to use for oncolytic virotherapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1635025881

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1635025881

Other Identifiers

ISSN

0929-1903

E-ISSN

1476-5500

DOI

10.1038/cgt.2014.51

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