Somatic mutations in arachidonic acid metabolism pathway genes enhance oral cancer post-treatment di...
Somatic mutations in arachidonic acid metabolism pathway genes enhance oral cancer post-treatment disease-free survival
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The arachidonic acid metabolism (AAM) pathway promotes tumour progression. Chemical inhibitors of AAM pathway prolong post-treatment survival of cancer patients. Here we test whether non-synonymous somatic mutations in genes of this pathway, acting as natural inhibitors, increase post-treatment survival. We identify loss-of-function somatic mutatio...
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Somatic mutations in arachidonic acid metabolism pathway genes enhance oral cancer post-treatment disease-free survival
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TN_cdi_proquest_miscellaneous_1639972920
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1639972920
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms6835