4-Hydroxynonenal, a Product of Lipid Peroxidation, Damages Cholinergic Neurons and Impairs Visuospat...
4-Hydroxynonenal, a Product of Lipid Peroxidation, Damages Cholinergic Neurons and Impairs Visuospatial Memory in Rats
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Hagerstown, MD: American Association of Neuropathologists, Inc
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Language
English
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Publisher
Hagerstown, MD: American Association of Neuropathologists, Inc
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Contents
The mechanisms that underlie cholinergic neuronal degeneration in Alzheimer disease (AD) are unclear, but recent data suggest that oxidative stress plays a role. We report that 4-hydroxynonenal (HNE), an aldehydic product of lipid peroxidation, damages and kills basal forebrain cholinergic neurons when administered intraparenchymally. Examination o...
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Full title
4-Hydroxynonenal, a Product of Lipid Peroxidation, Damages Cholinergic Neurons and Impairs Visuospatial Memory in Rats
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TN_cdi_proquest_miscellaneous_16422619
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_16422619
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ISSN
0022-3069
E-ISSN
1554-6578
DOI
10.1097/00005072-199803000-00007
