Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 tri...
Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense
About this item
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Author / Creator
Wang, Xing , Li, Yun , Liu, Shan , Yu, Xiaoliang , Li, Lin , Shi, Cuilin , He, Wenhui , Li, Jun , Xu, Lei , Hu, Zhilin , Yu, Lu , Yang, Zhongxu , Chen, Qin , Ge, Lin , Zhang, Zili , Zhou, Biqi , Jiang, Xuejun , Chen, She and He, Sudan
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
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Scope and Contents
Contents
The receptor-interacting kinase-3 (RIP3) and its downstream substrate mixed lineage kinase domain-like protein (MLKL) have emerged as the key cellular components in programmed necrotic cell death. Receptors for the cytokines of tumor necrosis factor (TNF) family and Toll-like receptors (TLR) 3 and 4 are able to activate RIP3 through receptor-intera...
Alternative Titles
Full title
Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_1642623808
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1642623808
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1412767111
