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EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway

EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1645779892

EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway

About this item

Full title

EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2015-01, Vol.517 (7533), p.219-222

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Unlike the limited post-injury neuronal regeneration in humans, severed axons in
C. elegans
can regenerate through a cellular fusion mechanism; this study identifies the molecular basis for this process which includes phosphatidylserine recognition and a role for specific molecules that also act in apoptosis.
Axonal fusion via an engulfmen...

Alternative Titles

Full title

EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1645779892

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1645779892

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature14102

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