Peroral gene therapy of lactose intolerance using an adeno-associated virus vector
Peroral gene therapy of lactose intolerance using an adeno-associated virus vector
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Contents
Gene therapy is usually reserved for severe and medically refractory disorders because of the toxicity, potential long-term risks and invasiveness of most gene transfer protocols. Here we show that an orally administered adeno-associated viral vector leads to persistent expression of a ß-galactosidase transgene in both gut epithelial and lamina pro...
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Full title
Peroral gene therapy of lactose intolerance using an adeno-associated virus vector
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TN_cdi_proquest_miscellaneous_16514064
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_16514064
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/2625
