Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness
Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In most metazoan nuclei, heterochromatin is located at the nuclear periphery in contact with the nuclear lamina, which provides mechanical stability to the nucleus. We show that in cultured cells, chromatin decompaction by the nucleosome binding protein HMGN5 decreases the sturdiness, elasticity and rigidity of the nucleus. Mice overexpressing HMGN...
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Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness
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TN_cdi_proquest_miscellaneous_1652396035
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1652396035
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms7138
