The Effect of Polymeric Excipients on the Physical Properties and Performance of Amorphous Dispersio...
The Effect of Polymeric Excipients on the Physical Properties and Performance of Amorphous Dispersions: Part I, Free Volume and Glass Transition
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Publisher
Boston: Springer US
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Language
English
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Publisher
Boston: Springer US
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Contents
Purpose
To investigate the structural effect of polymeric excipients on the behavior of free volume of drug-polymer dispersions in relation to glass transition.
Methods
Two drugs (indomethacin and ketoconazole) were selected to prepare amorphous dispersions with PVP, PVPVA, HPC, and HPMCAS through spray drying. The physical attributes of t...
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Full title
The Effect of Polymeric Excipients on the Physical Properties and Performance of Amorphous Dispersions: Part I, Free Volume and Glass Transition
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TN_cdi_proquest_miscellaneous_1652408886
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1652408886
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ISSN
0724-8741
E-ISSN
1573-904X
DOI
10.1007/s11095-014-1478-0