Glypican 3 overexpression in primary and metastatic Wilms tumors
Glypican 3 overexpression in primary and metastatic Wilms tumors
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Glypican 3 (GPC3), a heparan sulfate proteoglycan, plays a role in cell growth and differentiation. Mutations of the
GPC3
gene are responsible for Simpson-Golabi-Behmel syndrome, which is characterized by anomalies of postnatal overgrowth and an increased risk of developing pediatric malignancies, mostly Wilms tumor and liver cancer. In order...
Alternative Titles
Full title
Glypican 3 overexpression in primary and metastatic Wilms tumors
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Record Identifier
TN_cdi_proquest_miscellaneous_1652460345
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1652460345
Other Identifiers
ISSN
0945-6317
E-ISSN
1432-2307
DOI
10.1007/s00428-014-1669-4