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Glypican 3 overexpression in primary and metastatic Wilms tumors

Glypican 3 overexpression in primary and metastatic Wilms tumors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1652460345

Glypican 3 overexpression in primary and metastatic Wilms tumors

About this item

Full title

Glypican 3 overexpression in primary and metastatic Wilms tumors

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Virchows Archiv : an international journal of pathology, 2015-01, Vol.466 (1), p.67-76

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Glypican 3 (GPC3), a heparan sulfate proteoglycan, plays a role in cell growth and differentiation. Mutations of the
GPC3
gene are responsible for Simpson-Golabi-Behmel syndrome, which is characterized by anomalies of postnatal overgrowth and an increased risk of developing pediatric malignancies, mostly Wilms tumor and liver cancer. In order...

Alternative Titles

Full title

Glypican 3 overexpression in primary and metastatic Wilms tumors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1652460345

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1652460345

Other Identifiers

ISSN

0945-6317

E-ISSN

1432-2307

DOI

10.1007/s00428-014-1669-4

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