Molecular Characterization of the 128-kDa Immunodominant Antigen of Helicobacter pylori Associated w...
Molecular Characterization of the 128-kDa Immunodominant Antigen of Helicobacter pylori Associated with Cytotoxicity and Duodenal Ulcer
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Washington, DC: National Academy of Sciences of the United States of America
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English
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Washington, DC: National Academy of Sciences of the United States of America
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Helicobacter pylori has been associated with gastritis, peptic ulcer, and gastric adenocarcinoma. We report the nucleotide sequence and expression of an immunodominant antigen of H. pylori and the immune response to the antigen during disease. The antigen, named CagA (cytotoxin-associated gene A), is a hydrophilic, surface-exposed protein of 128 kD...
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Molecular Characterization of the 128-kDa Immunodominant Antigen of Helicobacter pylori Associated with Cytotoxicity and Duodenal Ulcer
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TN_cdi_proquest_miscellaneous_16527157
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_16527157
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.90.12.5791