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Molecular Characterization of the 128-kDa Immunodominant Antigen of Helicobacter pylori Associated w...

Molecular Characterization of the 128-kDa Immunodominant Antigen of Helicobacter pylori Associated w...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_16527157

Molecular Characterization of the 128-kDa Immunodominant Antigen of Helicobacter pylori Associated with Cytotoxicity and Duodenal Ulcer

About this item

Full title

Molecular Characterization of the 128-kDa Immunodominant Antigen of Helicobacter pylori Associated with Cytotoxicity and Duodenal Ulcer

Publisher

Washington, DC: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1993-06, Vol.90 (12), p.5791-5795

Language

English

Formats

Publication information

Publisher

Washington, DC: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Helicobacter pylori has been associated with gastritis, peptic ulcer, and gastric adenocarcinoma. We report the nucleotide sequence and expression of an immunodominant antigen of H. pylori and the immune response to the antigen during disease. The antigen, named CagA (cytotoxin-associated gene A), is a hydrophilic, surface-exposed protein of 128 kD...

Alternative Titles

Full title

Molecular Characterization of the 128-kDa Immunodominant Antigen of Helicobacter pylori Associated with Cytotoxicity and Duodenal Ulcer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_16527157

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_16527157

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.90.12.5791

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