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Acute inhibition of casein kinase 1δ/ε rapidly delays peripheral clock gene rhythms

Acute inhibition of casein kinase 1δ/ε rapidly delays peripheral clock gene rhythms

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1654675372

Acute inhibition of casein kinase 1δ/ε rapidly delays peripheral clock gene rhythms

About this item

Full title

Acute inhibition of casein kinase 1δ/ε rapidly delays peripheral clock gene rhythms

Publisher

Boston: Springer US

Journal title

Molecular and cellular biochemistry, 2015-01, Vol.398 (1-2), p.195-206

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

Circadian rhythms are generated through a transcription-translation feedback loop involving clock genes and the casein kinases CSNK1D and CSNK1E. In this study, we investigated the effects of the casein kinase inhibitor PF-670462 (50 mg/kg) on rhythmic expression of clock genes in the liver, pancreas and suprachiasmatic nucleus (SCN) as well as pla...

Alternative Titles

Full title

Acute inhibition of casein kinase 1δ/ε rapidly delays peripheral clock gene rhythms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1654675372

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1654675372

Other Identifiers

ISSN

0300-8177

E-ISSN

1573-4919

DOI

10.1007/s11010-014-2219-8

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