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Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma

Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1654685974

Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma

About this item

Full title

Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2014-06, Vol.46 (6), p.583-587

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Shumpei Ishikawa and colleagues report the identification of recurrent gain-of-function mutations in
RHOA
in diffuse-type gastric carcinomas.
Diffuse-type gastric carcinoma (DGC) is characterized by a highly malignant phenotype with prominent infiltration and stromal induction. We performed whole-exome sequencing on 30 DGC cases and found...

Alternative Titles

Full title

Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1654685974

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1654685974

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng.2984

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