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Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons...

Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1654690760

Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance

About this item

Full title

Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2014-06, Vol.46 (6), p.558-566

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Piero Carninci and colleagues report the discovery of a large class of noncoding RNAs, non-annotated stem cell transcripts (NASTs), which are implicated in the regulation of stem cell properties. The authors identify 8,873 mouse and 3,042 human NASTs and functionally validate 4 as having an important role in the maintenance of pluripotency.
The...

Alternative Titles

Full title

Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1654690760

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1654690760

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng.2965

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