The role of alpha sub(2)-adrenoceptor antagonism in the anti-cataleptic properties of the atypical n...
The role of alpha sub(2)-adrenoceptor antagonism in the anti-cataleptic properties of the atypical neuroleptic agent, clozapine, in the rat
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Author / Creator
Kalkman, HO , Neumann, V , Hoyer, D and Tricklebank, MD
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English
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The mechanism underlying the anticataleptic properties of the atypical neuroleptic agent, clozapine, has been investigated in the rat. The close structural analogues of clozapine, loxapine (0.1 mg/kg s.c.) and iso-clozapine (1 and 3 mg/kg s.c.) induced catalepsy in rats. In contrast, clozapine and the regio-isomer of loxapine, isoloxapine (up to 10...
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Full title
The role of alpha sub(2)-adrenoceptor antagonism in the anti-cataleptic properties of the atypical neuroleptic agent, clozapine, in the rat
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TN_cdi_proquest_miscellaneous_16550168
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_16550168
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ISSN
0007-1188