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The role of alpha sub(2)-adrenoceptor antagonism in the anti-cataleptic properties of the atypical n...

The role of alpha sub(2)-adrenoceptor antagonism in the anti-cataleptic properties of the atypical n...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_16550168

The role of alpha sub(2)-adrenoceptor antagonism in the anti-cataleptic properties of the atypical neuroleptic agent, clozapine, in the rat

About this item

Full title

The role of alpha sub(2)-adrenoceptor antagonism in the anti-cataleptic properties of the atypical neuroleptic agent, clozapine, in the rat

Journal title

British journal of pharmacology, 1998-08, Vol.124 (7), p.1550-1556

Language

English

Formats

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Scope and Contents

Contents

The mechanism underlying the anticataleptic properties of the atypical neuroleptic agent, clozapine, has been investigated in the rat. The close structural analogues of clozapine, loxapine (0.1 mg/kg s.c.) and iso-clozapine (1 and 3 mg/kg s.c.) induced catalepsy in rats. In contrast, clozapine and the regio-isomer of loxapine, isoloxapine (up to 10...

Alternative Titles

Full title

The role of alpha sub(2)-adrenoceptor antagonism in the anti-cataleptic properties of the atypical neuroleptic agent, clozapine, in the rat

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_16550168

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_16550168

Other Identifiers

ISSN

0007-1188

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