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Retinoblastoma gene mutations detected by whole exome sequencing of Merkel cell carcinoma

Retinoblastoma gene mutations detected by whole exome sequencing of Merkel cell carcinoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1660401214

Retinoblastoma gene mutations detected by whole exome sequencing of Merkel cell carcinoma

About this item

Full title

Retinoblastoma gene mutations detected by whole exome sequencing of Merkel cell carcinoma

Publisher

New York: Elsevier Inc

Journal title

Modern pathology, 2014-08, Vol.27 (8), p.1073-1087

Language

English

Formats

Publication information

Publisher

New York: Elsevier Inc

More information

Scope and Contents

Contents

Merkel cell carcinoma is a highly aggressive cutaneous neuroendocrine tumor that has been associated with Merkel cell polyomavirus in up to 80% of cases. Merkel cell polyomavirus is believed to influence pathogenesis, at least in part, through expression of the large T antigen, which includes a retinoblastoma protein-binding domain. However, there...

Alternative Titles

Full title

Retinoblastoma gene mutations detected by whole exome sequencing of Merkel cell carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1660401214

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1660401214

Other Identifiers

ISSN

0893-3952

E-ISSN

1530-0285

DOI

10.1038/modpathol.2013.235

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