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Genetic modifiers of EGFR dependence in non-small cell lung cancer

Genetic modifiers of EGFR dependence in non-small cell lung cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1660402156

Genetic modifiers of EGFR dependence in non-small cell lung cancer

About this item

Full title

Genetic modifiers of EGFR dependence in non-small cell lung cancer

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (52), p.18661-18666

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Significance Non-small cell lung cancers (NSCLCs) harboring mutations in the epidermal growth factor receptor ( EGFR ) gene are often singularly reliant on EGFR activity for tumor cell survival, but the genetic basis for this dependence is not fully understood. In this study, we have performed a screen to identify a spectrum of kinase genes whose o...

Alternative Titles

Full title

Genetic modifiers of EGFR dependence in non-small cell lung cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1660402156

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1660402156

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1412228112

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