Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease
About this item
Full title
Author / Creator
Lunnon, Katie , Smith, Rebecca , Hannon, Eilis , De Jager, Philip L , Srivastava, Gyan , Volta, Manuela , Troakes, Claire , Al-Sarraj, Safa , Burrage, Joe , Macdonald, Ruby , Condliffe, Daniel , Harries, Lorna W , Katsel, Pavel , Haroutunian, Vahram , Kaminsky, Zachary , Joachim, Catharine , Powell, John , Lovestone, Simon , Bennett, David A , Schalkwyk, Leonard C and Mill, Jonathan
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Alzheimer's disease (AD) is a chronic neurodegenerative disorder characterized by progressive neuropathology and cognitive decline. Here the authors describe an epigenome-wide association study (EWAS) of human post-mortem brain samples across multiple independent AD cohorts. They find consistent hypermethylation of the
ANK1
gene associated wi...
Alternative Titles
Full title
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease
Authors, Artists and Contributors
Author / Creator
Smith, Rebecca
Hannon, Eilis
De Jager, Philip L
Srivastava, Gyan
Volta, Manuela
Troakes, Claire
Al-Sarraj, Safa
Burrage, Joe
Macdonald, Ruby
Condliffe, Daniel
Harries, Lorna W
Katsel, Pavel
Haroutunian, Vahram
Kaminsky, Zachary
Joachim, Catharine
Powell, John
Lovestone, Simon
Bennett, David A
Schalkwyk, Leonard C
Mill, Jonathan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1664194600
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1664194600
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.3782
