The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of...
The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Senescent T cells have increased activity of the mitogen-activated protein kinase p38. Akbar and colleagues show that such cells lack the canonical and alternative p38-activation pathways and instead induce kinase AMPK–dependent autophosphorylation of p38.
In T lymphocytes, the mitogen-activated protein kinase (MAPK) p38 regulates pleiotropic fu...
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The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells
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TN_cdi_proquest_miscellaneous_1664202883
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1664202883
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2981
