Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
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Author / Creator
De Jager, Philip L , Srivastava, Gyan , Lunnon, Katie , Burgess, Jeremy , Schalkwyk, Leonard C , Yu, Lei , Eaton, Matthew L , Keenan, Brendan T , Ernst, Jason , McCabe, Cristin , Tang, Anna , Raj, Towfique , Replogle, Joseph , Brodeur, Wendy , Gabriel, Stacey , Chai, High S , Younkin, Curtis , Younkin, Steven G , Zou, Fanggeng , Szyf, Moshe , Epstein, Charles B , Schneider, Julie A , Bernstein, Bradley E , Meissner, Alex , Ertekin-Taner, Nilufer , Chibnik, Lori B , Kellis, Manolis , Mill, Jonathan and Bennett, David A
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Aging can lead to cognitive decline associated with neural pathology and Alzheimer's disease (AD). Here the authors scan the methylation status of CpGs across the entire genome of brain samples from aged subjects in an epigenome-wide association study (EWAS). Several loci, including ANK1, were associated with AD pathology, gene expression and AD ge...
Alternative Titles
Full title
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
Authors, Artists and Contributors
Author / Creator
Srivastava, Gyan
Lunnon, Katie
Burgess, Jeremy
Schalkwyk, Leonard C
Yu, Lei
Eaton, Matthew L
Keenan, Brendan T
Ernst, Jason
McCabe, Cristin
Tang, Anna
Raj, Towfique
Replogle, Joseph
Brodeur, Wendy
Gabriel, Stacey
Chai, High S
Younkin, Curtis
Younkin, Steven G
Zou, Fanggeng
Szyf, Moshe
Epstein, Charles B
Schneider, Julie A
Bernstein, Bradley E
Meissner, Alex
Ertekin-Taner, Nilufer
Chibnik, Lori B
Kellis, Manolis
Mill, Jonathan
Bennett, David A
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1664205157
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1664205157
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.3786
