Thrombomodulin alleviates murine GVHD in association with an increase in the proportion of regulator...
Thrombomodulin alleviates murine GVHD in association with an increase in the proportion of regulatory T cells in the spleen
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Author / Creator
Ikezoe, T , Yang, J , Nishioka, C and Yokoyama, A
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Recombinant human soluble thrombomodulin (rTM), a potent anticoagulant, has been used for the treatment of disseminated intravascular coagulation in Japan since 2008. Interestingly, rTM possesses anti-inflammatory and cytoprotective functions. This study examined whether rTM alleviates GVHD in a murine hematopoietic SCT (HSCT) model. Use of rTM sig...
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Full title
Thrombomodulin alleviates murine GVHD in association with an increase in the proportion of regulatory T cells in the spleen
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TN_cdi_proquest_miscellaneous_1664207474
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1664207474
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ISSN
0268-3369
E-ISSN
1476-5365
DOI
10.1038/bmt.2014.208