The OCT4 pseudogene POU5F1B is amplified and promotes an aggressive phenotype in gastric cancer
The OCT4 pseudogene POU5F1B is amplified and promotes an aggressive phenotype in gastric cancer
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Author / Creator
Hayashi, H , Arao, T , Togashi, Y , Kato, H , Fujita, Y , De Velasco, M A , Kimura, H , Matsumoto, K , Tanaka, K , Okamoto, I , Ito, A , Yamada, Y , Nakagawa, K and Nishio, K
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
POU5F1B
(POU domain class 5 transcription factor 1B), a processed pseudogene that is highly homologous to
OCT4
, was recently shown to be transcribed in cancer cells, but its clinical relevance and biological function have remained unclear. We now show that
POU5F1B
, which is located adjacent to
MYC
on human chromosome 8q24, is...
Alternative Titles
Full title
The OCT4 pseudogene POU5F1B is amplified and promotes an aggressive phenotype in gastric cancer
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Record Identifier
TN_cdi_proquest_miscellaneous_1664208398
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1664208398
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2013.547
