ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype
ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype
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Full title
Author / Creator
Junankar, Simon , Baker, Laura A. , Roden, Daniel L. , Nair, Radhika , Elsworth, Ben , Gallego-Ortega, David , Lacaze, Paul , Cazet, Aurélie , Nikolic, Iva , Teo, Wee Siang , Yang, Jessica , McFarland, Andrea , Harvey, Kate , Naylor, Matthew J. , Lakhani, Sunil R. , Simpson, Peter T. , Raghavendra, Ashwini , Saunus, Jodi , Madore, Jason , Kaplan, Warren , Ormandy, Christopher , Millar, Ewan K. A. , O’Toole, Sandra , Yun, Kyuson and Swarbrick, Alexander
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Basal-like breast cancer (BLBC) is a heterogeneous disease with poor prognosis; however, its cellular origins and aetiology are poorly understood. In this study, we show that inhibitor of differentiation 4 (ID4) is a key regulator of mammary stem cell self-renewal and marks a subset of BLBC with a putative mammary basal cell of origin. Using an ID4...
Alternative Titles
Full title
ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype
Authors, Artists and Contributors
Author / Creator
Baker, Laura A.
Roden, Daniel L.
Nair, Radhika
Elsworth, Ben
Gallego-Ortega, David
Lacaze, Paul
Cazet, Aurélie
Nikolic, Iva
Teo, Wee Siang
Yang, Jessica
McFarland, Andrea
Harvey, Kate
Naylor, Matthew J.
Lakhani, Sunil R.
Simpson, Peter T.
Raghavendra, Ashwini
Saunus, Jodi
Madore, Jason
Kaplan, Warren
Ormandy, Christopher
Millar, Ewan K. A.
O’Toole, Sandra
Yun, Kyuson
Swarbrick, Alexander
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1667344714
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1667344714
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms7548
