Immune complexes regulate bone metabolism through FcRγ signalling
Immune complexes regulate bone metabolism through FcRγ signalling
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Autoantibody production and immune complex (IC) formation are frequently observed in autoimmune diseases associated with bone loss. However, it has been poorly understood whether ICs regulate bone metabolism directly. Here we show that the level of osteoclastogenesis is determined by the strength of FcRγ signalling, which is dependent on the relati...
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Immune complexes regulate bone metabolism through FcRγ signalling
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TN_cdi_proquest_miscellaneous_1668238230
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1668238230
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms7637